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Grinding or clenching of the teeth (similar to that seen in bruxism) may bepresent in patients with jaw closing dystonia and may also be seen in patients withsecondary dystonia, such as that seen in patients with cerebral palsy or traumatic braininjury. Symptoms ofapathy include a loss of interest or motivation, as wellas decreased initiation of behavior

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(1998) Cognitive test per-formance and crash risk in an older driver population. The myocardium is the thickest layerof the heart, made up of contractile cardiac muscle cells.

Primitive acupuncture needles dating back to around 1000 BChave been discovered in archeological finds of the Shan dynasty in China.Other similar healing practices involve the use of stones to massage overcertain points on the body; these date back even further, perhaps as faras four to ten thousand years. In addition to thetraditional PICO, in the PESICO rubric “E” stands for communication environments (or“setting-related issues”) and “S” stands for the relevant stakeholders, such as parents andfamily members, friends, and employers, whose perspectives and attitudes “may directlyor indirectly influence the decision.” Others have modified the original PICO template byappending an optional “T” for time frame (Fineout-Overholt, & Stillwell, 2011; Haynes,Sackett, Guyatt, & Tugwell, 2006).

NCPAP was shown to beeffective in treating infants with RDS (Gittermannet al.

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